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Things in order of importance
Primary
Tech skill
Feats
DR changes to double ME.
Biotics powers
Combat powers
tech powers
shields
Go though all attack powers and double damage of most.
Biotics powers
Combat powers
tech powers
Change all mines and power all based explosives to be grenades.
Secondary
add limitation to tech powers, some require omnitool(not available at start)
Tactical rules
vehicle rules
Race changes to 3 feats
Environments
Class level 30 abilities
Tertiary
Items
Crafting
World info
Prepare high tech gear (ME weapons*2dam etc)
prepare adventures